Immunological Tolerance Methods and Protocols [Paperback]

Immunological Tolerance: Methods and Protocols is a comprehensive guide to the techniques currently used for culturing and characterising the cell types responsible for imposing self-tolerance and the experimental models employed to study their function both in vitro and in vivo. This guide is aimed at AIDS researchers, immunologists, transplant surgeons/specialists, and biotechnologists.

Immunological Tolerance: Methods and Protocols is a comprehensive guide to the techniques currently used for culturing and characterising the cell types responsible for imposing self-tolerance and the experimental models employed to study their function both in vitro and in vivo.Immunological Tolerance: Methods and ProtocolsTable of ContentsIntroduction1. Frontiers of Immunological ToleranceGiorgio Raimondi, Heth Turnquist & Angus ThomsonUniversity of Pittsburgh Medical Center, Thomas E Starzl Transplantation Institute, Pittsburgh, USACell Types Contributing to Immunological Tolerance2. Case Study: Balancing Tolerance & Immunity: The Role of Dendritic Cell & T Cell SubsetsElena Chklovskaia & Barbara Fazekas de St GrothCentenary Institute of Cancer Medicine & Cell Biology, University of Sydney, Sydney, Australia3. Differentiation of Dendritic Cell Subsets from Mouse Bone MarrowLudovica BrunoThe Institute of Cancer Research, London, UK4. Genetic Modification of Dendritic Cells through the Directed Differentiation of Embryonic Stem CellsPaul J. Fairchild, Kathleen F. Nolan, &Herman WaldmannSir William Dunn School of Pathology, University of Oxford, Oxford, UK5. Generation of Immunocompetent T Cells from Embryonic Stem CellsRen?e F. de Pooter & Juan-Carlos Zu?iga-Pfl?ckerDept of Immunology, University of Toronto, Sunnybrook & Women's Research Institute, Toronto, Canada6. Isolation, Expansion and Characterization of Human Natural and Adaptive Regulatory T CellsSilvia Gregori, Rosa Bacchetta,Laura Passerini, Megan K. Levings lc+