Immunology and Its Impact on Infections in Surgery [Paperback]

In this book, the recent developments in immunology and the impact on the treatment of infections in critical care and in surgery are presented, also describing how cellular immunology influences clinical treatment. This information helps in understanding the pathogenesis of infections in surgery and critical care. The impact of a standard treatment such as antibiotic therapy is evaluated and possible future therapy modalities outlined. This book will be of interest to clinicians and immunologists as scientists of both specialties have contributed to the book.In this book, the recent developments in immunology and the impact on the treatment of infections in critical care and in surgery are presented, also describing how cellular immunology influences clinical treatment. This information helps in understanding the pathogenesis of infections in surgery and critical care. The impact of a standard treatment such as antibiotic therapy is evaluated and possible future therapy modalities outlined. This book will be of interest to clinicians and immunologists as scientists of both specialties have contributed to the book.Animal Models.- Yersinia enterocolitica Infection in Mice: A Possible Experimental Model for the Immunobiology of Gram-Negative Infections.- Development of a New Animal Model for Chronic Abscess-Forming Peritonitis.- Tolerance to Endotoxin in an Animal Model of Acute Pancreatitis Is Associated with Improved Cellular Immune Function.- Prolonged and Recurrent Endotoxemia in Domestic Pigs: A First Step Toward a Porcine Model of Human Multiple Organ Failure?.- Endotoxin, Interferon-?, Biopterin, Serum Phospholipase A2 Activity, and ?-Endorphin as Differentiation Factors and Their Correlations in the Acute Immune Response During Lethal Gram-Negative Sepsis in LEW Rats.- Gene Expression.- The Effects of Burn Injury on Cytokine Production and Gene Expression.- Genomic Fingerprinting for the Evaluation of Epidemic Processes.- Interleukin-2 Receptor Expression Is Ulc"