This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.?
Part I: Innate immunity
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The role of cytokine responses during influenza virus pathogenesis and potential therapeutic options
John R. Teijaro
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Innate immune sensing and response to influenza?
Mohan S. Maddur and Bali Pulendran
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The NS1 protein: a multitasking virulence factor?
Juan Ayllon and Adolfo Garcia-Sastre
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Role of NK cells in influenza infection?
Stacey Shultz-Cherry
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Host detection and the stealthy phenotype in influenza virus infection
Pradyot Dash and Paul G. Thomas
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Part II: Vaccines and adaptive immunity
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Inactivated and adjuvanted influenza vaccines
Giuseppe Del Giudice and Rino Rappuoli
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Live attenuated influenza vaccine
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