This reference book compiles the most recent developments in experimental and clinical research and practice in one comprehensive edition. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
Cellular Responses in Sepsis.- The Role of Toll-like Receptors in Sepsis.- The Emerging Role of RAGE in Sepsis.- Oxidative Stress in Sepsis: Implications on Liver Protein Patterns and Analysis via Modified Proteomics Technology.- HSP90: The Unsung Villain of Sepsis?.- The Role of Extracellular Heat Shock Proteins in Cellular Inflammation and Injury.- Quantitative in vivo Protein Synthesis as a Measure of Immune Function.- Fluid Resuscitation and Immunomodulation in the Critically III.- Cellular Dysfunction.- Mitochondrial Dysfunction and Critical Illness Myopathy.- Lactic Acidosis and Hyperlactatemia.- Cardiovascular Dysfunction.- Physiology and Pathophysiology of the Natriuretic Peptide System.- Heart Failure as a Co-Morbidity in the ICU.- The Vascular Bed during Critical Illness: Evaluation in Animal Models.- Hemodynamic Monitoring.- Intensive Care Echocardiography.- Intrathoracic Blood Volume: Clinical Applications.- Hemodynamic Management Guided by Esophageal Doppler.- Less Invasive Cardiac Output Monitoring: Characteristics and Limitations.- Pulse Pressure Analysis.- Pulse Pressure Variations in Managing Fluid Requirement: Beware the Pitfalls!.- Minimally Invasive Hemodynamic Monitoring Using the Pressure Recording Analytical Method.- Coagulopathies.- Thrombotic Microangiopathy Syndrome in the ICU.- Altered Functionality of von Willebrand Factor in Sepsis and Thrombocytopenia Potential Role of the vWF Cleaving Protease ADAMTS-13.- Coagulopathy in the Critically Injured Patient.- Critical Bleeding in Blunt Trauma Patients.- Trauma: Bleeding, Coagulopathy, and Blood ComponelÓm