Interstitial Fibrosis in Heart Failure [Paperback]

Interstitial Fibrosis in Heart Failure, edited by Francisco J. Villarreal, M.D., Ph.D., provides a timely and integrative review of the basics of cardiac extracellular matrix structure. Topics covered include how cardiac remodeling influences its disposition, abundance and function; possible non-invasive techniques for diagnosis; and potential drug-based or molecular therapeutic strategies that may interrupt or even reverse the course of the development of cardiac fibrosis.

This resource for both clinicians and scientists aims to cover state-of-the-art findings relevant to cellular and molecular processes underlying cardiac fibrosis including basic elements of structure, function, diagnosis and treatment.

Interstitial Fibrosis in Heart Failure, edited by Francisco J. Villarreal, M.D., Ph.D., provides a timely and integrative review of the basics of cardiac extracellular matrix structure. Topics covered include how cardiac remodeling influences its disposition, abundance and function; possible non-invasive techniques for diagnosis; and potential drug-based or molecular therapeutic strategies that may interrupt or even reverse the course of the development of cardiac fibrosis.

This resource for both clinicians and scientists aims to cover state-of-the-art findings relevant to cellular and molecular processes underlying cardiac fibrosis including basic elements of structure, function, diagnosis and treatment.

Architecture of the Normal and Remodeled Heart.- The Architecture of the Heart: Myocyte Organization and the Cardiac Extracellular Matrix.- Extracellular Matrix and Cardiac Remodeling.- Pro-Inflammatory Cytokines and Cardiac Extracellular Matrix: Regulation of Fibroblast Phenotype.- Pharmacology of G-Protein-linked Signaling in Cardiac Fibroblasts.- Diagnostic Tools for the Identification of Myocardial Fibrosis and Changes in Ventriculal.