This 1992 volume examines the important relationship, initially studied in 1871 by Bowditch, between the strength of the heartbeat and the interval between beats.Originally published in 1992, this volume looks in detail at the important relationship, initially studied in 1871 by Bowditch, between the strength of the heartbeat and the interval between beats. The book draws together the work and experience of leading international research workers in this field.Originally published in 1992, this volume looks in detail at the important relationship, initially studied in 1871 by Bowditch, between the strength of the heartbeat and the interval between beats. The book draws together the work and experience of leading international research workers in this field.Originally published in 1992, this volume looks in detail at the important relationship, initially studied in 1871 by Bowditch, between the strength of the heartbeat and the interval between beats. The book draws together the work and experience of leading international research workers in this field. Collectively, the contributors illuminated the underlying mechanisms involved, their expression in both isolated muscle and the intact heart, and speculate on further avenues of research. The volume will be of interest to cardiologists, physiologists and all those concerned with the function of the heart.Contributors; Introduction; Part I: 1. On the peculiarities of excitability which the fibres of the cardiac muscle show translated by J. Schaefer, W. Deppert, R. K. Lie, B. Lohff, M. I. M. Noble with a historical note H. P. Bowditch; Part II. The General Process: 2. The interval-strength relationship of cardiac muscle: past, present, and future D. G. Allen; 3. A model for interval-force phenomena: unresolved issues I. C. Cooper and M. I. M. Noble; Part III. Cellular Processes Underlying Interval-Force Behaviour and their Control: 4. Relationships between intracellular free calcium and force with changes of interval D.lC„