Proteomics provides an introductory insight on proteomics, discussing the basic principles of the field, how to apply specific technologies and instrumentation, and example applications in human health and diseases. With helpful study questions, this textbook presents an easy to grasp and solid overview and understanding of the principles, guidelines, and especially the complex instrumentation operations in proteomics for new students and research scientists. Written by a leader in proteomics studies,
Proteomics offers an expert perspective on the field and the future of proteomics.
FOREWORD. PREFACE.
ABOUT THE AUTHOR.
CHAPTER 1 HISTORICAL PERSPECTIVES.
1.1. Introduction to Proteomics.
1.2. Proteome and Proteomics.
1.3. Genetics of Proteins.
1.4. Molecular Biology of Genes and Proteins.
1.5. Protein Chemistry Before Proteomics.
References.
Further Reading.
CHAPTER 2 PROTEOMICS—RELATION TO GENOMICS, BIOINFORMATICS.
2.1. Genomics.
2.2. Bioinformatics and Computational Biology.
References.
Further Reading.
CHAPTER 3 METHODOLOGY FOR SEPARATION AND IDENTIFICATION OF PROTEINS AND THEIR INTERACTIONS.
3.1. Separation of Proteins Via a Multidimensional Approach.
3.2. Determination of the Primary Structure of Proteins.
3.3. Determination of the 3D Structure of a Protein.
3.4. Determination of the Amount of Proteins.
3.5. Structural and Functional Proteomics.
References.
Further Reading.
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