Issues in Clinical Epileptology A View from the Bench [Hardcover]

This book is dedicated to Dr. Philip A. Schwartzkroin. The book has a novel format because it is not intended to be a set of reviews. Instead, it is an effort to explore important topics in the epilepsy research field. Because articles are written by leaders in the field who have years of experience and individuals with diverse expertise, articles are likely to have a long-lasting impact and be relevant for both epileptologists and neuroscientists. Authors address topics that are important, unresolved questions in the field of epilepsy research, drawing on available data from both the bench and the clinic to support their points. A given topic is addressed by one or more authors, each writing from his/her own unique perspective. For all of the individuals who have been trained or worked with Philip Schwartzkroin in the past and/or have appreciated his contributions to the epilepsy field, this volume is an excellent way to celebrate his achievements and look to the ways they have moved the field forward and continue to stimulate its growth.

Preface
Foreword Jerome Engel, Marc A. Dichter?

Part I ?Seizures, epileptiform activities and regional localization

1 How can we identify ictal and interictal abnormal activity? Robert Fisher, Helen Scharfman, Marco de Curtis

2 How can we translate epileptiform activity in vitro into something that is clinically relevant? Uwe Heinemann, Kevin Staley

3 What is the importance of abnormal background activity in seizure generation? Richard Staba, Gregory Worrell

4 What is a seizure focus? J. Victor Nadler, Dennis Spencer

5 What is a seizure network? Very fast oscillations at the interface between normal and epileptic brain Roger Traub, Mark? Cunningham, Miles Whittington