Arterial Chemoreception From Molecules to Systems [Hardcover]

Arterial chemoreceptors are unique structures which continuously monitor changes in arterial blood oxygen, carbon dioxide, glucose, and acid. Alterations in these gases are almost instantaneously sensed by arterial chemoreceptors and relayed into a physiological response which restores blood homeostasis.Arterial Chemoreception contains updated material regarding the physiology of the primary arterial chemoreceptor; the carotid body. Moreover, this book also explores tantalizing evidence regarding the contribution of the aortic bodies, chromaffin cells, lung neuroepithelial bodies, and brainstem areas involved in monitoring changes in blood gases. Furthermore this collection includes data showing the critical importance of these chemoreceptors in the pathophysiology of human disease and possible therapeutic treatments.This book is a required text for any researcher in the field of arterial chemoreception for years to come. It is also a critical text for physicians searching for bench-to-bedside treatments for heart failure, sleep apnea, and pulmonary hypertension.

The Role of Hypoxia-Inducible Factors in Oxygen Sensing by the Carotid Body  Invited Article.- Neuronal Mechanisms of Oxygen Chemoreception: An Invertebrate Perspective  Invited Article.-

Peripheral Chemoreceptors in Air- versus Water- Breathers? Invited Article.- Sex-specific Effects of Daily Gavage With a Mixed Progesterone and Glucorticoid Receptor Antagonist on Hypoxic Ventilatory Response in Newborn Rats.- Age-Dependent Changes in Breathing Stability in Rats.- Dose Dependant Effect of Progesterone on Hypoxic Ventilatory Response in Newborn Rats.- Postnatal Hyperoxia Impairs Acute Oxygen Sensing of Rat Glomus Cells by Reduced Membrane Depolarization.- Erythropoietin and the Sex-Dimorphic Chemoreflex Pathway  Invited Article.- Time-course of Ventilation, Arterial and Pulmonary CO₂ Tension During CO₂ Increase in Humans.- OxygenlCš