Advances in BioChirality [Hardcover]

Chirality is a fundamental, persistent, but often overlooked feature of all living organisms on the molecular level as well as on the macroscopic scale. The high degree of preference for only one of two possible mirror image forms in Nature, often called biological homochirality is a puzzling, and not yet fully understood, phenomenon.

This book covers biological homochirality from an interdisciplinary approach - contributions range from synthetic chemists, theoretical topologists and physicists, from palaeontologists and biologists to space scientists and representatives of the pharmaceutical and materials industries.

Topics covered include - theory of biochirality, origins of biochirality, autocatalysis with amplification of chirality, macroscopic (present) biochirality, fossil records of chiral organisms - paleochirality, extraterrestrial origin of chirality, exceptions to the rule of biological homochirality, D-amino acids, chemical transfer of chirality, PV effects, and polarised radiation chemistry.

Selected chapter headings: Preface. (C. Bartolacelli). Dimensions of Biological Homochirality (G. Pályi et al.). Theory of Biological Homochirality: Chirality, Symmetry Deficiency, and Electron-Cloud Holography in the Shape Analysis of Biomolecules (P.G. Mezey). On the Biological Advantage of Chirality (G. Gilat). Possible Mechanisms for Spontaneous Production of Enantiomeric Excess (D.Z. Lippmann, J. Dix). Search for the Origin of Homochirality of Biomolecules (L. Keszthelyi). The Role of Homochirality in Evolution (Z. Nansheng). Asymmetric Autocatalysis and Biomolecular Chirality (K. Soai, T. Shibata). Left-right Asymmetry in Animal Embryogenesis (M. Levin). Evolutionary Origin of Asymmetry in Early Metazoans (J. Dzik). Application of Amino Acid Racemization in Fossil Pleistocene Vertebrate and Invertebrate Analysis. Preservation of Proteins and Amino Acids (T.lSz