Preface. Sponsors. List of Participants.Gender-Specificity of Gamete Susceptibilities to Exposures. 1. Female-Specific Reproductive Toxicities Following Preconception Exposure to Xenobiotics; J.B. Bishop. 2. Overview of Male Mediated Developmental Toxicity; D. Anderson.Exposures and Effects: Occupational and Environmental. 3. Epidemiologic Evidence on Biological and Environmental Male Factors in Embryonic Loss; J.P. Bonde, et al. 4. Mechanisms of Male Mediated Developmental Toxicity Induced by Lead; E.K. Silbergeld, et al. 5. Paternal Exposure to Known Mutagens and Health of the Offspring: Ionizing Radiation and Tobacco Smoke; D.A. Savitz. 6. FISH (Fluorescence In Situ Hybridization) to Detect Effects of Smoking, Caffeine, and Alcohol on Human Sperm Chromosomes; W.A. Robbins.Markers of Sperm Damage and Germ Line Genotoxicity. 7. Sperm Nuclear DNA Damage in the Human; D. Sakkas, et al. 8. The Human Spermtozoon: Not Waving but Drowning; J.R. Aitken, D. Sawyer. 9. Model Systems for Studying Germ Cell Mutagens: From Flies to Mammals; E.W. Vogel, M.J.M. Nivard. 10. Germline Mutation Induction at Mouse and Human Tandem Repeat DNA Loci; Y.E. Dubrova. 11. PAINT/DAPI Analysis of Mouse Zygotes to Detect Paternally Transmitted Chromosomal Aberrations; F. Marchetti, A.J. Wyrobek.Exposures and Effects: Causes of Cancer Consequences of Treatment. 12. Paternal Occupation and Childhood Cancer; A.F. Olshan, E. van Wijngaarten. 13. Radiation and Malformations in a Murine Model; W.-U. M?ller. 14. Mechanisms of Action of Cyclophosphamide asa Male-Mediated Developmental Toxicant; B. Robaire, B.F. Hales. 15. Chromosome Abnormalities in Human Sperm; R.H. Martin.Pregnancy Outcome. 16. Distinguishing Between Fertilization Failure and Early Pregnancy Loss When Identifying Male-Mediated Adverse Pregnancy Outcomes; S.D. Perrault. 17. ICSI, Male Pronuclear Remodeling and Cell Cycle Checkpoints; L. Hewitson, et al. 18. Increased Incidence of Malformations in the Offspring of Male Mice PrenatallylcC