Application of Transition Metal Catalysts in Organic Synthesis [Paperback]

Homogeneous catalysis is an important strategy for the synthesis of high-valued chemicals. L. Brandsma has carefully selected and checked the experimental procedures illustrating the catalytic use of copper, nickel, and palladium compounds in organic synthesis. All procedures are on a preparative scale, make economic use of solvents and catalysts, avoid toxic substances and have high yields.Homogeneous catalysis is an important strategy for the synthesis of high-valued chemicals. L. Brandsma has carefully selected and checked the experimental procedures illustrating the catalytic use of copper, nickel, and palladium compounds in organic synthesis. All procedures are on a preparative scale, make economic use of solvents and catalysts, avoid toxic substances and have high yields.1 Catalysts, Ligands and Reagents.- 1.1 Catalysts.- 1.1.1 Copper Halides.- 1.1.1.1 Solubilization of Copper(I) Halides.- 1.1.2 Nickel Catalysts.- 1.1.2.1 Nickel(II)bromide?bis(triphenylphosphane).- 1.1.2.2 Nickel(II)chloride?bis(triphenylphosphane).- 1.1.2.3 Nickel(II)chloride?1,3-bis(diphenylphosphino) propane.- 1.1.2.4 Nickel(II)chloride?1,2-bis(diphenylphosphino)ethane.- 1.1.2.5 Nickel(II)chloride?1,4-bis(diphenylphosphino)butane.- 1.1.2.6 Nickel(II)chloride?1,1?-bis(diphenylphosphino)ferrocene.- 1.1.2.7 Nickel(II)bromide?1,1?-bis(diphenylphosphino)ferrocene.- 1.1.2.8 trans-Chloro(1-naphthyl)bis(triphenylphosphane)nickel.- 1.1.2.9 trans-Bromo(1-naphthyl)bis(triphenylphosphane)nickel and trans-Bromo(phenyl)bis(triphenyl-phosphane)nickel.- 1.1.3 Palladium Catalysts.- 1.1.3.1 Palladium(II)chloride?bis(acetonitrile).- 1.1.3.2 Palladium(II)chloride?bis(benzonitrile).- 1.1.3.3 Palladium(II)chloride?bis(triphenylphosphane).- 1.1.3.4 Palladium(II)chloride?1,4-bis(diphenylphosphino)butane.- 1.1.3.5 Palladium(II)chloride?1,1?-bis(diphenylphosphino)ferrocene.- 1.1.3.6 Tetrakis(triphenylphosphane)palladium(0).- 1.1.3.7 Tris(dibenzylideneacetone)dipalladium(0)?chloroform.- 1.2 Ligands.- 1.2.1 1,n-Bis(dil#Æ