Biochemical Basis and Therapeutic Implications of Angiogenesis [Hardcover]

This book covers the latest developments in the therapeutic implications of angiogenesis, ranging from angiogenesis in the brain, angiogenesis in cancer, angiogenesis role in atherosclerosis and heart disease as well as metabolic disorders and?peripheral vascular disease. The book is comprehensive in its coverage?of angiogenesis in a diverse set of diseases and examines the role of cellular and subcellular structures during the development of angiogenesis.?Well-organized and thorough, this is an ideal book for researchers and biomedical engineers working in the field of therapeutic implications of angiogenesis.

This book also:

Covers the basics of the physiology of angiogenesis, including VEGF pathways in angiogenesis, integr

Details the role of angiogenesis in atherosclerosis and heart disease, including vascular endothelial growth factor and atherosclerotic plaque progression as well as angiogenesis and heart failure

Illustrates in detail brain angiogenesis after stroke and the relationship between angiogenesis and Alzheimer's disease

Leading authorities on the biochemistry of this complex physiological process explain its critical role in human growth and development as well as the pathogenesis of cancer, heart disease, and other morbidities. The book fully updates the current literature.

Part1. Molecular Mechanisms in Angiogenesis.- 1.Endothelial Growth Factor Receptors in Angiogenesis.- 2.The Role of Integrins in Angiogenesis.- 3.Toll-Like Receptors in Angiogenesis.- 4.Vascular Stem Cells in Regulation of Angiogenesis.- 5.Role of Transforming Growth Factor Beta Family in Angiogenesis.- 6.Angiogenesis-based Strategy by Hepatocyte Growth Factor for the Treatment of Ischemic Organ Diseases: From Biology to Clinical Trials.- 7.Functions of MicrolCž