Bioinformatics of Genome Regulation and Structure [Paperback]

- The data gathered can be used to solve a wide range of problems - for basic science and applied scienceBioinformatics of Genome Regulation and Structure covers:

-regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition;
-large-scale genome analysis and functional annotation;
-gene structure detection and prediction;
-comparative and evolutionary genomics;
-computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure-function organization of genomic DNA, RNA, and proteins;
-gene networks, signal transduction pathways, and genetically controlled metabolic pathways: principles of organization, operation, and evolution;
-data warehousing, knowledge discovery and data mining; and,
-analysis of basic patterns of genome operation, organization, and evolution.

The data presented may be used while solving a wide range of problems, both basic and applied, in various directions of molecular biology, molecular genetics, biotechnology, pharmacogenetics, pharmacology, and adjacent fields of medicine, veterinary, and agrobiology.1. Computational Genomics.- Nucleosomal DNA Organization: An Integrated Information System.- Using Change in Local DNA Sequence Complexity as a Pointer to the Mechanism of Mutagenesis in Inherited Disease.- Properties of Insertion Regions of Drosophila LTR Retrotransposons.- Compositional Asymmetries and Predicted Origins of Replication of the SaccharomycesCerevisiae Genome.- Revealing and Functional Analysis of tRNA-Like Sequences in Various Genomes.- Type-Specific Features of the Structure of the tRNA Gene Promoters.- Mathematical Tools for Regulatory Signals Extraction.- Argo_Viewer: A Package for Recognition and Analysis of Regulatory Elements in Eukaryoticló#