Cell Culture Engineering VI [Hardcover]

The latest edition in this continuing series includes the newest advances in the rapidly evolving field of animal cell culture, genetic manipulations for heterologous gene expression, cell line enhancements, improved bioreactor designs and separations, gene therapy manufacturing, tissue engineering, anti-apoptosis strategies and cell cycle research. The contents include new research articles as well as critical reviews on emerging topics such as viral and viral-like agent contamination of animal cell culture components. These papers were carefully selected from contributions by leading academic and industrial experts in the biotechnology community at the recent Cell Culture Engineering VI Meeting in San Diego, USA, 1998. However, the book is not merely a proceedings.
Audience: Biochemical engineers, cell biologists, biochemists, molecular biologists, immunologists and other disciplines related to cell culture engineering, working in the academic environment and the biotechnology or pharmaceutical industry.Cell therapy in kidney failure; H.D. Hunes, et al. Improved bicistronic mammalian expression vectors using expression augmenting sequence element (EASE); T.L. Aldrich, et al. Effects on growth behavior in continuous hybridoma cell cultures: The role of viral contamination; A. Hawerkamp, et al. Isolation, characterization and recombinant protein expression in Veggie-CHO: A serum-free CHO host cell line; B. Rasmussen, et al. Collective experiences of adventitious viruses of animal-derived raw materials and what can be done about them; S.J. Wessmann, R.L. Levings. An overview of viral and viral-like agents in cell culture systems; J.C. Petricciani. New adenovirus vectors for protein production and gene transfer; B. Massie, et al. Modulation of cell cycle progression and of antibody production in mouse hybridomas by a nucleotide analogue; F. Franek, et al. Engineering Chinese hamster ovary (CHO) cells to achlÃ9