In this volume the impact of cell culture models ondermatological research is discussed by scientists frommedicine, physiology, biology, pharmacology,and pharmacy.The book includes the following topics: orthology andpathology of the skin, differentiation of keratinocytes andfibroblasts, problems of the cultivation of melanocytes,biochemistry of pigment metabolism, models for wound healingand tissue renewal, fibroblast function and metabolism ofcollagen, models for the investigation of ageing as well asmodels for pharmacological and toxicologial tests.Thus, a wide arch is spanned, from basic problems withcultivation and characterization of cell cultures toexamples of application. Dermatologists as well as cellbiologists will benefit from this publication.In this volume the impact of cell culture models ondermatological research is discussed by scientists frommedicine, physiology, biology, pharmacology,and pharmacy.The book includes the following topics: orthology andpathology of the skin, differentiation of keratinocytes andfibroblasts, problems of the cultivation of melanocytes,biochemistry of pigment metabolism, models for wound healingand tissue renewal, fibroblast function and metabolism ofcollagen, models for the investigation of ageing as well asmodels for pharmacological and toxicologial tests.Thus, a wide arch is spanned, from basic problems withcultivation and characterization of cell cultures toexamples of application. Dermatologists as well as cellbiologists will benefit from this publication.1. Models in Orthology and Pathology.- Development of a Cell Culture System to Detect and Analyze Pathogenicity of Autoantibodies Directed to Nuclear Antigens.- Cell Cultures of Fetal Human Skin Are Suitable Models for the Investigation of Mitogenic Activity in Psoriasis Sera.- Influence of Human Seló–