Computational Methods in Synthetic Biology [Paperback]

This volume provides complete coverage of the computational approaches currently used in Synthetic Biology.? Chapters focus on computational methods and algorithms for the design of bio-components, insight on CAD programs, analysis techniques, and distributed systems. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.

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Authoritative and practical, Computational Methods in Synthetic Biology serves as a guide to plan in silico the in vivo or in vitro construction of a variety of synthetic bio-circuits.

Part I: Component Design

1. Computational Protein Design Methods for Synthetic Biology

Pablo Carbonell and ?Jean-Yves Trosset

Denis Selnihhin and Ebbe Sloth Andersen

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3. Computational Design Of RNA Parts, Devices, and Transcripts With Kinetic Folding Algorithms Implemented On Multiprocessor Clusters

Tim Thimmaiah, William E. Voje Jr., and James M. Carothers

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4. Regulatory RNA Design Through Evolutionary Computation And Strand Displacement

William Rostain, Thomas E. Landrain, Guillermo Rodrigo, and Alfonso Jaramillo

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Part II: Circuit Design

5.? Programming Languages for Circuit Design

Michael Pedersen and Boyan Yordanov

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6. Kappa Rule-Based Modelling in Synthetic Biology

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7. Modular Design Of Synthetl#¼