Contemporary Nephrology Volume 2 [Paperback]

1 Membrane Transport: Ion Transport in the Kidney and Anuran EpitheliaMechanisms of Aldosterone Action.- 1. Introduction.- 2. The General Effects of Aldosterone.- 2.1. General Effects of Aldosterone in Anuran Epithelia.- 2.2. General Effects of Aldosterone in the Nephron.- 2.3. General Effects of Aldosterone on Other Mammalian Epithelia.- 3. Mechanisms for the Regulation of Epithelial Ion Transport.- 3.1. The Transport of Sodium Ions.- 3.2. The Transport of Potassium Ions.- 3.3. Proton Transport.- 4. Advances in Explaining the Mechanism of Aldosterone Action.- 4.1. Effect of Aldosterone on Metabolism.- 4.2. Effect of Aldosterone on Na, K-ATPase.- 4.3. Effects of Aldosterone on Ionic Conductances.- 4.4. Effects of Aldosterone on the Synthesis of Specific Proteins.- 4.5. Effects of Aldosterone on Plasma Membranes and Lipid Metabolism.- 5. Summary.- References.- 2 Renal Hemodynamics and Sodium Chloride Excretion.- 1. Autoregulation of Renal Blood Flow and Glomerular Filtration Rate.- 2. Factors That Influence Renal Hemodynamics.- 2.1. Neural Control.- 2.2. Vasoactive Agents.- 3. Sodium Excretion.- 3.1. Aldosterone in the Regulation of Sodium Excretion.- 3.2. Neural Reflex Control of Sodium Excretion.- 3.3. Intrarenal Hormone Action on Sodium Excretion.- 3.4. Physical Factors in the Regulation of Sodium Excretion.- 4. Chloride Transport.- References.- 3 Renal Metabolism.- 1. Introduction.- 2. Methodological Considerations.- 2.1. The Isolated Perfused Rat Kidney.- 2.2. Isolated Renal Tubules from Proximal and Distal Segments.- 2.3. Brush Border and Basolateral Membrane Preparations.- 2.4. Renal Cell Culture Techniques.- 2.5. Nuclear Magnetic Resonance (NMR).- 3. Biochemistry of Tubular Transport.- 3.1. Mechanisms of Transport.- 3.2. Relationships to Oxidative Metabolism.- 4. Selected Aspects of Intermediary Metabolism.- 4.1. Role of Calcium and Calcium Transport.- 4.2. H+ and Intracellular pH.- 4.3. Gluconeogenesis.- 5. Coupling of Active Ion Transport and Aerobic Metabl£3