DNA Damage and Repair Volume 2 DNA Repair in Higher Eukaryotes [Paperback]

Cutting edge reviews by leading researchers illuminate key aspects of DNA repair in mammalian systems and its relationship to human genetic disease and cancer. Major topics include UV and X-Ray repair, repair of chemical damage, recombinational repair, mismatch repair, transcription-repair coupling, and the role of DNA repair in disease prevention. Extensive up-to-date references and rigorous peer-review of each chapter make this volume definitive and bring it to the active frontiers of research.Cutting edge reviews by leading researchers illuminate key aspects of DNA repair in mammalian systems and its relationship to human genetic disease and cancer. Major topics include UV and X-Ray repair, repair of chemical damage, recombinational repair, mismatch repair, transcription-repair coupling, and the role of DNA repair in disease prevention. Extensive up-to-date references and rigorous peer-review of each chapter make this volume definitive and bring it to the active frontiers of research.Overview, Philip Hanawalt . DNA Photolyases, Akira Yasui and Andr? P. M. Eker . Cellular Responses to Methylation Damage, Russell O. Pieper . Exogenous Carcinogen-DNA Adducts and Their Repair in Mammalian Cells, Anthony Dipple and Leonora J. Lipinski . Nature of Lesions Formed by Ionizing Radiation, John F. Ward . Mammalian Enzymes for Preventing Mutations Caused by Oxidation of Guanine Nucleotides, Mutsuo Sekiguchi and Hiroshi Hayakawa .Biochemistry of Mammalian DNA Mismatch Repair, A-Lien Liu . Short Patch Mismatch Repair in Mammalian CellsPaola Gallinari, Petra Nedderman, and Josef Jiricny . Role of HMG and Other Proteins in Recognition of Cisplatin DNA Damage, Paul C. Billings and Edward N. Hughes .TFIIH: A Transcription Factor Involved in DNA Repair and Cell-Cycle Regulation, Vincent Moncollin, Paul Vichi, and Jean-Marc Egly . DNA Polymerase Involvement in DNA Repair, Samuel H. Wilson and Rakesh K. Singhal . Cellular Functions of Mammalian DNA Ligases, Alan E. Tompkinson, Jinl3K