Drug Delivery [Paperback]

In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering todays options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.

This overview on modern approaches to drug targeting covers todays options for specific carrier systems allowing successful drug treatment at problematic sites of the body and enabling practitioners to increase the benefit-risk ratio to the optimum level.

In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering todays options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.

Fundamentals.- Passive and Active Drug Targeting: Drug Delivery to Tumors as an Example.- Nanoparticle Technologies for Cancer Therapy.- Biosensing and Drug Delivery at the Microscale.- Devices.- Lipid Nanoparticles: Effect on Bioavailability and Pharmacokinetic Changes.- Viral Vectors for Gene Transfer: Current Status of Gene Therapeutics.- Pulmonary Drug Delivery: lS.