From Enzyme Models to Model Enzymes RSC [Hardcover]

Enzymes are the (impeccably green) catalysts that make the Chemistry of Life run smoothly and efficiently, and understanding how they work has been a major challenge for Biological Science for many years. Despite tremendous progress our understanding still fails the ultimate, practical test - of designing and making artificial systems with catalytic efficiencies to rival those of natural enzymes. Artificial enzymes has been a hot topic for many years, but until now no textbook has been devoted specifically to this subject. From Enzyme Models to Model Enzymes is the first to provide a critical introduction to, and overview of, this exciting area. It is aimed at both students and more senior researchers with interests in the field.This book provides a convenient entry point into the chemistry for the biochemist and molecular biologist, and for the chemist an entr?e into the biological methods that are of rapidly growing importance in this and a number of other topical areas.Anthony J. Kirby is Professor (Emeritus) of Bioorganic Chemistry at the University of Cambridge. He has over 40 years teaching and research experience in the area and has authored over 300 papers and 3 books. Florian Hollfelder has been lecturing in Biochemistry since 2001. He has a total of 15 years teaching and research experience at Cambridge, Stanford & Harvard and has authored more than 30 papers.This introduction to the exciting area of artificial enzymes is suitable for students and more senior researchers.Designing artificial systems with catalytic efficiencies to rival those of natural enzymes is one of the great challenges facing science today. Our current level of understanding fails the basic, practical test - designing and making artificial systems with catalytic efficiencies to rival those of natural enzymes. Chemists and bio-scientists are well aware of this problem, and artificial enzymes have been a hot topic for many years. However, until now, there has been no book devoted l3,