Immunology of Pregnancy [Paperback]

This book covers in detail contemporary hypotheses and studies related to the immunology of implantation and provides a practical approach for the application of basic reproductive immunology research to pregnancy complications such as preeclampsia, pre-term labor and IUGR. Provides complete and up to date review of current knowledge of the role of the immune system during pregnancy and the interactions between the placenta and the maternal immune system.

Reproductive Immunology is a growing area in both immunology and reproductive sciences and is helping us to better understand several complications of pregnancy. Immunology of Pregnancy is the first book to give a complete and up to date review of our knowledge related to the role of the immune system during pregnancy and the interactions between the placenta and the maternal immune system.

This new title covers in detail all the different hypotheses and studies related to the immunology of implantation and provide a practical approach for the application of basic reproductive immunology research to pregnancy complications such as preeclampsia, pre-term labor and IUGR.

Evolution of the Mammalian Reproductive Tract and Placentation.- Toll-Like Receptors and Pregnancy.- IL-10 and Pregnancy.- Th1/Th2 Balance of the Implantation Site in Humans.- The Regulation of Human Trophoblast Apoptosis and Survival during Pregnancy.- Macrophages and Pregnancy.- Potential Role of Glucocorticoids in the Pathophysiology of Intrauterine Growth Restriction (IUGR).- NK Cells and Pregnancy.- The Role of Corticotropin-Releasing Hormone (CRH) on Implantation and Immunotolerance of the Fetus.- Indoleamine 2,3 Dioxygenase-Dependent T Cell Suppression and Pregnancy.- Leukemia Inhibitory Factor in Reproduction.- Characterization of Human Dendritic Cells at the Materno-Fetal Interface.- MHC Molecules of the Preimplantation Embryo and Trophoblast.- Actions of Seminal PlaslƒL