Inflammatory Bowel Disease From Bench to Bedside [Paperback]

Inflammatory Bowel Disease: From Bench to Bedside is a detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders is explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.

Inflammatory Bowel Disease: From Bench to Bedside is a detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders are explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.

Preface. Section 1: The Laboratory Bench. 1. Introduction: Inflammatory Bowel Diseases: From Bench to Bedside; S. R. Targan, F. Shanahan, L. C. Karp. 2. The Changing Faces of Crohn's Disease and Ulcerative Colitis; A. Ekbom. 3. Genetics of Inflammatory Bowel Disease; J.I. Rotter, H. Yang. 4. Experimental Mouse Models of Inflammatory Bowel Disease: New Insights into Pathogenic Mechanisms; C.O. Elson. 5. The Normal Intestinal Mucosa - A State of `Controlled' Inflammation; C. Fiochi. 6. The Lymphocyte/ Epithelial/ Bacterial Interface; R. Hershberg and R. Blumberg. 7. The Mucosal Inflammatory Response I: Cytokines and Chemokines; F. Cominelli. 8. Role of the Microcirulation in Chronic Gut Inflammation; M. B. Grisham, F. S. Laroux and D. N. Granger. 9. Remission, Relapse, Intestinal Heall£å