I. Signal Transduction Mechanisms.- The Amplifying Transduction Cascade Triggered by Rhodopsin in Visual Receptor Cells Biochemical and Biophysical Approaches.- Inositol Lipid Metabolism: Generation of Second Messengers.- Bradykinin-Induced Inositol Phosphate Metabolism in Human A431 Epidermoid Carcinoma Cells.- Mechanisms of Signal Transduction by Growth Factor Receptors.- Study of the Mechanism of Hormone Induced Desensitization and Internalization of Beta-Adrenergic Receptors.- Immunological Stimulation of Mast Cells Degranulation: Role of Cytosolic pH, Na+ and Ca2+ Ions.- II. Receptor Characteristics.- Nicotinic Acetylcholine Receptor and Myasthenia Gravis Studied by Anti-Receptor Monoclonal Antibodies.- Mutant Receptors for Low Density Lipoprotein in Familial Hypercholesterolemia.- Calcium and Guanosine Nucleotide Modulation of Melanotropin Receptor Function and Adenylate Cyclase in the M2R Melanoma Cell Line.- Structure-Function Studies of Growth-Factor Receptors.- Molecular Interactions of Ganglioside Receptors with Tetanotoxin on Solid Support, Aqueous Solutions and Natural Membranes.- Interaction of Cholera Toxin with its Receptor the Monosialoganglioside GM1: a Fluorescence Study.- Incorporation of GABA/Benzodiazepine Receptors into Natural Brain Lipid Liposomes: Biochemical Characterization.- Interaction of Laminin with Cell Membranes.- Solubilization of the Fusicoccin Receptor and a Protein Kinase from Highly Purified Plasma Membrane from Oat Roots.- III. Transport and Energetics.- Bacteriorhodopsin: Molecular Biology of the Light Activated Proton and Divalent Cation Receptor in the Membranes of Halobacteria.- Influence of the Chromophore Retinal and the State of Aggregation on the Proton/Hydroxyl Ion Flux across Bacteriorhodopsin.- Complete Tracking of Proton Flow in Thylakoids: the Unit Conductance of CFO is Greater than 10 fS.- Essential Role of Arginine Residues in the Interaction of F0 with F1 in Escherichia Coli ATP Synthase.- Solute Transport acrolă