Neural Mechanisms of Anesthesia [Paperback]

Leading investigators critically evaluate the latest information on how anesthetics work at the molecular, cellular, organ, and whole animal level. These distinguished experts review anesthetic effects on memory, consciousness, and movement and spell out in detail both the anatomic structures and physiological processes that are their likely targets, as well as the cellular and molecular mechanisms by which they operate. Comprehensive and authoritative, Neural Mechanisms of Anesthesia draws together and critically reviews all the recent research on anesthetic mechanisms, highlighting the precise routes along which these substances operate, and how this deeper understanding will lead to the design of effective drugs free ofundesirable side effects.Leading investigators critically evaluate the latest information on how anesthetics work at the molecular, cellular, organ, and whole animal level. These distinguished experts review anesthetic effects on memory, consciousness, and movement and spell out in detail both the anatomic structures and physiological processes that are their likely targets, as well as the cellular and molecular mechanisms by which they operate. Comprehensive and authoritative, Neural Mechanisms of Anesthesia draws together and critically reviews all the recent research on anesthetic mechanisms, highlighting the precise routes along which these substances operate, and how this deeper understanding will lead to the design of effective drugs free ofundesirable side effects.I. IntroductionThe Development of Concepts of Mechanisms of AnesthesiaDonald Caton and Joseph F. AntogniniII. Anesthesia, Consciousness, and MemoryMechanisms of Consciousness with Emphasis on the Cerebral Cortical ComponentG. Bryan YoungAnesthesia Meets Memory: Tools for Critical AppraisalRobert A. VeselisIII. Sleep, Coma, and Anesthesia-Similarities and DifferencesSleep and AnesthesiaJohn KeiferPossible Relationships of Anesthetic Coma and Pathological Disorders of Consciousnessl35