Practical Immunopathology of the Skin [Paperback]

Bruce R. Smoller, md, concisely reviews for practitioners and students alike the science of immunopathology, its many basic laboratory tools, and their multiple diagnostic uses in actual clinical case studies. The author presents in an easily digestible form a dictionary of antibody probes, summarizing for each antibody the targeted antigen and its cellular function, its diagnostic utility, and, when available, its sensitivities and specificities for identifying various neoplasms. Real clinical cases from the author's practice demonstrate the benefits of immunopathology.Bruce R. Smoller, md, concisely reviews for practitioners and students alike the science of immunopathology, its many basic laboratory tools, and their multiple diagnostic uses in actual clinical case studies. The author presents in an easily digestible form a dictionary of antibody probes, summarizing for each antibody the targeted antigen and its cellular function, its diagnostic utility, and, when available, its sensitivities and specificities for identifying various neoplasms. Real clinical cases from the author's practice demonstrate the benefits of immunopathology.I. IntroductionOverview.Immunoperoxidase: The TechniqueII. Antibody DirectoryEpithelial MarkersMesenchymal Markers (Nonhematopoietic)Hematopoietic MarkersMelanocyte MarkersNeuroectodermal (Other than Melanocytic) and Neuroendocrine MarkersAntibodies Used to Identify Infectious Diseases. Markers Useful in Detecting Metastatic DiseaseIII. VignettesVignettesIndex This book contains the best discussion on the subject and I would recommend it as a requirement for dermatologists and pathologists. This field has become more and more technical and understanding this subject is a necessity for anyone dealing with skin pathology - Doody's Health Sciences Book Review Journal

The book fulfills its stated aim of providing dermatologists, in training or active practice, with a working repertoire of useful antibodies. Those replÓD