The Adrenocortical Hormones [Paperback]

Professor Helen Wendler Deane Markham, 19171966.- 9: Control of Aldosterone Secretion.- Methods Used to Measure the Rate of Aldosterone Secretion.- A. Adrenocortical Histology.- B. Sodium and Potassium Excretion.- C. Direct Measurement of Aldosterone in Body Fluids.- I. Bioassay.- II. Chemical Identification.- III. Isotope Derivative and Dilution Methods.- IV. Special Problems in the Measurement of Aldosterone in Urine.- V. Special Problems in the Measurement of Aldosterone in Adrenal-Venous Blood.- VI. Measurement of Aldosterone in Peripheral Blood.- D. Determination of Secretion Rate by Dilution of Isotopic Aldosterone.- Effccts of Changes in Plasma Electrolyte Levels on Aldosterone Secretion.- ACTH and the Control of Aldosterone Secretion.- A. Effect of Hypophysectomy on Adrenal Histology.- B. Effcct of Hypophysectomy on Aldosterone Secretion.- C. Effect of ACTH on Aldosterone Secretion.- D. Possible Indirect Effects of ACTH on Aldosterone Secretion.- E. Control of ACTH Secretion.- The Renin-Angiotensin System and the Control of Aldosterone Secretion.- A. The Effect of Renin and Angiotensin II on Aldosterone Secretion.- I. Mechanism of Action of Angiotensin II on the Adrenal Cortex.- II. Effects of Endogenous Renin.- B. Other Effects of Angiotensin II.- I. Variations in Pressor Response.- II. Effects on the Kidney.- C. Metabolism of Angiotensin II.- D. Renin.- E. Comparative Physiology of the Renin-Angiotensin System.- F. The Juxtaglomerular Apparatus as the Source of Renin.- G. Stimulation of Renin Secretion.- I. Methods for Measuring Renin and Angiotensin II in Body Fluids.- II. Other Indices of Renin Secretion.- III. Stimuli Affecting Renin Secretion and Their Mode of Action.- 1. Role of the Pressure Gradient Across the JG Cells.- 2. Chronic Renal Hypertension.- 3. Effects of Changes in Pulse Pressure.- 4. Effect of Renal Arteriolar Constriction.- 5. Effects of Other Stimuli.- 6. Other Theories of the Control of Renin Secretion.- Interactions Between ACTH andl#-