Investigations on anatomical specimens have demonstrated that the subchondral mineralization does indeed show regular distribution patterns from which conclusions about the mechanical situation within an individual joint may be drawn. Since radiographical densitometry and histological methods are only available for determining the adaptive reaction of the bone to the mechanical situation in a joint after death, the information obtained applies only to an end situation and tells us nothing about the development of the changes with time. Furthermore, investigations carried out on human specimens by radiographical densitometry mostly apply to samples of a particular age, since such specimens can be acquired only from departments of pathology, forensic medicine or anatomy.Investigations on anatomical specimens have demonstrated that the subchondral mineralization does indeed show regular distribution patterns from which conclusions about the mechanical situation within an individual joint may be drawn. Since radiographical densitometry and histological methods are only available for determining the adaptive reaction of the bone to the mechanical situation in a joint after death, the information obtained applies only to an end situation and tells us nothing about the development of the changes with time. Furthermore, investigations carried out on human specimens by radiographical densitometry mostly apply to samples of a particular age, since such specimens can be acquired only from departments of pathology, forensic medicine or anatomy.1 Introduction (Review of Literature).- 1.1 Preliminary Remarks.- 1.2 General Mechanisms for the Regulation of the Morphology of Bone Tissue.- 1.3 Morphology of the Subchondral Bone.- 1.3.1 Definition of the Term Subchondral Bone.- 1.3.2 Structure of Normal Subchondral Bone.- 1.3.2.1 Architecture.- 1.3.2.2 Vascularity of the Subchondral Bone Plate.- 1.3.2.3 Thickness of the Subchondral Bone Plate.- 1.3.2.4 Density Distribution in the Suls2