Chemistry of Proteolysis [Paperback]

A first edition of this book appeared in Russian language in 1983. Since those days the interest in proteolytic enzymes has acquired a new impulse due to advances in genetic engineering techniques, which facilitated structural and func?? tional studies of the enzymes. Much more data on a crucial role of proteases in biological processes in norm and pathology are available now. Information that appeared in the past 8 years prompted a renewal of the book and furnishing a supplement especially made for the English edition. The book retains the presentation of the previous edition and yet enlarges the scope to cover the methods for site-directed mutagenesis of amide hydrolases, catalyti?? cally active antibodies, etc. I have tried to preserve the book as a means of reference for the reader. A list of enzymes has been expanded and the biblio?? graphy up to 1990 enlarged by half as much. I am grateful to the translators T. E. Chernichko, N. 1. Loboda and my co?? worker Dr. S. L. Alexandrov for their assistance in the preparation ofthis edition and I feel happy that my book is now available for enzymologists abroad.A first edition of this book appeared in Russian language in 1983. Since those days the interest in proteolytic enzymes has acquired a new impulse due to advances in genetic engineering techniques, which facilitated structural and func?? tional studies of the enzymes. Much more data on a crucial role of proteases in biological processes in norm and pathology are available now. Information that appeared in the past 8 years prompted a renewal of the book and furnishing a supplement especially made for the English edition. The book retains the presentation of the previous edition and yet enlarges the scope to cover the methods for site-directed mutagenesis of amide hydrolases, catalyti?? cally active antibodies, etc. I have tried to preserve the book as a means of reference for the reader. A list of enzymes has been expanded and the biblio?? graphy up to 1990 enlarlӜ