Connexins The Gap Junction Proteins [Paperback]

Gap-junction proteins, connexins are important cellular entities that regulate various facets of cellular physiology. The connexins constitute large family of proteins. The present book provides basic overview about various aspects of connexin proteins. The book has tried to touch the fundamental aspects of connexin family. This book will be useful to broad audience that includes under-and post-graduate students, research scholars, clinicians, etc. The reference section at the end of the book will be helpful for those who seek to know deeper details about this family of proteins.

1. Introduction.- 2. Historical and Topological Perspective of Connexins.- 3. Molecular Components and Nomenclature of Gap Junctions.- 4. General Cell Biology of Connexins.- 5. Genomic Organization of Connexins.- 6. Transcriptional Regulation of the Connexin Gene.- 7. Epigenetic Regulation of Connexins.- 8. Translation Regulation of Connexins.- 9. Interaction Partners of Connexin Proteins.- 10. Tissue Distribution of Connexins.- 11. Connexin Functions.- 12. Connexin Mutations and Disease.- 13. Suggested Reading.

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Dr. M.U. Hussain earned his PhD from International Graduate School of Neuroscience (IGSN), Ruhr University, Bochum, Germany, under the supervision of renowned gap-junction neurobiologist, Prof. Dr. Med Rolf Dermietzel. He worked as a post-doctoral research fellow in the department of Neuroanatomy and Molecular Brain Research. During his doctoral and post-doctoral work, Dr Hussain gained research experience in various aspects of modern biology. His doctoral work earned him the highest European honour of Summa Cum Lauda. To the credit of Dr. Hussain are many international papers, published in well reputed journals. Presently, Dr. Hussain is senior Assistant Professor at the Department of Biotechnology, University of Kashmir. His main responsibilities in the department are research and post-graduate teaching.lÕ