Spider Venoms [Hardcover]

This volume provides an overview of the biochemical characterization, structure-function studies, proteomics, bioinformatics, molecular biology, transcriptomics and genomics of various spider species. The book also covers our current knowledge of venom components, toxins and their modes of action. The first section of Spider Venom includes contributions regarding the wide diversity of spider venom components and depicts some of their biological effects (antimicrobial, ion channel modulators, insecticides, this includes peptide and non-peptide toxins), and emphasizes spiders of public health importance. The second section covers transcriptomes, proteomes (and peptidomics), bioinformatics and molecular dynamics. The last section describes antimicrobial, insecticidal toxins, envenomation and the medical potential of spider venoms.

Spider venoms are a great and extensive source of bioactive compounds, and as such form a boundless and bountiful area awaiting discovery. It is by virtue of dedicated scientists that new toxins are discovered and that new insights arise, leading the way towards the investigation of their pharmacological effects, and hopefully, as a consequence, arriving at the discovery of venom components as new drug candidates.

This comprehensive reference collects important biochemical, biomedical and clinical insights in Toxinology, spanning biochemistry, molecular biology, anatomy and pharmacology, and discussing the potential for venom-based drugs. Volume 3 covers Spider Venom.Anticancer Potential of Spider Venom. - Antimicrobial Peptides in Spider Venoms. - Antimicrobial, Insecticides, Analgesics, and Hyalurodinases from the Venom Glands of Brachypelma Spiders. - Bioecology of Spiders with Emphasis in Spiders of Public Health Importance. - Hippasa Spider, Biology, Envenomation, Toxin Profiles, Biological Functions: A Review. - Identifying Insect Protein ReceptlCr