Exosomes, Stem Cells and MicroRNA Aging, Cancer and Age Related Disorders [Hardcover]

This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries. 

The book contains some basic introductory material that is useful for students/researchers who are new to this area of research, & concisely written and provide a useful collection of references for readers who want to delve into some of the topics in further detail. The excellent figures and summary tables throughout the book help readers to comprehend the material. (Michael J. Fay, Doody's Book Reviews, May 24, 2019)

Dr. Karl Mettinger received his M.D. from the University of Lund in Sweden and his Ph.D. in in the field of Hematology/Neurology from Karolinska Institute/Karolinska University Hospital in Stockholm, where he served as Associate Professor of Neurology. He was a cofounder and President of the Swedish Stroke Society with currently over 10,000 members. He is currently President and CEO of Cellastra Inc.in San Francisco. For more than 30 years he has served as an executive in the lifelƒ