Antibiotic Pharmacodynamics [Paperback]

This text offers state of the art contributions written by world renown experts which provide an extensive background on specific classes of antibiotics and summarize our understanding as to how these antibiotics might be optimally used in a clinical situation.? The book explores pharmacodynamics methods for anti-infective agents, pharmacodynamics of antibacterial agents and non-antibacterial agents, as well as pharmacodynamic considerations and special populations. As part of the Methods in Pharmacology and Toxicology series, chapters include detailed insight and practical information for the lab.

Comprehensive and cutting-edge, Antibiotic Pharmacodynamics serves as an ideal reference for scientists investigating advances in antibiotic pharmacodynamics now finding their way into the antibiotic development process used for licensing new antibiotics.

1. General Concepts of Pharmacodynamics for Anti-Infective Agents

??????????? Johan W. Mouton

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2. In Vitro Pharmacodynamic Models to Evaluate Anti-Infective Pharmacodynamics

??????????? Warren Rose

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3. Animal Models to Evaluate Anti-Infective Pharmacodynamics

??????????? Alexander J. Lepak and David R. Andes

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4. Pharmacodynamic Issues in Antibiotic Combinations

??????????? Zackery P. Bulman, Ryan C. Dillon, Sarith M. Saju, Neang S. Ly, Gauri G. Rao, Phillip J. Bergen, Cornelia B. Landersdorfer, Alan Forrest, Juergen B. Bulitta, and Brian T. Tsuji

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5. Methodologies for Protein Binding Determination in Anti-Infective Agents

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???????? Jatinder Kaur Mukker, Ravi Shankar Prasad lcÅ