Joint Destruction in Arthritis and Osteoarthritis [Paperback]

Cartilage destruction in arthritis and osteoarthritis.- Osteoarthritis in the human knee: A dynamic process of cartilage matrix degradation, synthesis and reorganization.- Experimental arthritis models in the study of the mechanisms of articular cartilage loss in rheumatoid arthritis.- Altered structure-function relationships for articular cartilage in human osteoarthritis and an experimental canine model.- Mechanisms of cartilage destruction in joint inflammation.- Immunopathology.- Synovial fluid analyses detect and differentiate proteoglycan metabolism in canine experimental models of osteoarthritis and disuse atrophy.- Humoral and cell-mediated sensitivity to cartilage constituents in mice with antigen-induced arthritis.- In vitro and in vivo effects of proteoglycan fractions in adjuvant treated rats.- Are antibodies reactive with chondrocyte proteins enriched in synovial fluids of patients with rheumatoid arthritis?.- Joint loading and cartilage metabolism.- The metabolic response of articular cartilage to abnormal mechanical loading induced by medial or lateral meniscectomy.- Effects of long-term running exercise on canine femoral head articular cartilage.- Human and bovine articular cartilage loading measured with a new resistive sensor: Effects of protease degradation and osteoarthritis.- Cytokines and growth factors.- Possible role of IL-1 in arthritis: Effects of prostaglandins in the regulation of IL-1 synthesis and actions.- Degradative and repair responses of cartilage to cytokines and growth factors occur via distinct pathways.- Does TGF-? protect articular cartilage in vivo?.- Human rheumatoid synovial cells (HRSC) in culture express TGF-? receptors and are growth stimulated by the factor.- Variable TGF-? receptor expression regulates TGF-? responses of articular chondrocytes.- Proteases and their inhibitors.- Proteolytic degradation in human articular cartilage: Its relationship to Stromelysin.- The inhibition of interleukin 1-stimulated cartilage prló¢