Macromolecular Crystallography Protocols, Volume 2 Structure Determination [Hardcover]

In the decade since publication of the first edition this book, the field has seen several major developments. These developments have both accelerated the pace of structure determination and made crystallography accessible to a broader range of investigators. Volume I is dedicated to crystallization and ways to increase the odds of obtaining crystals in macromolecules. Volume 2 covers both computational methods for characterizing crystals and solving structures.

In the decade since publication of the first edition of Crystallographic Methods and Protocols the field has seen several major developments that have both accelerated the pace of structure determination and made crystallography accessible to a broader range of investigators. Volume I, Preparation and Crystallization of Macromolecules is dedicated to the crystallization and ways to increase the odds of obtaining crystals in macromolecules, while Volume 2, Structure Determination, covers both computational methods for characterizing crystals and solving structures.TABLE OF CONTENTS VOLUME 2HUMANA PRESS-CRYSTALLOGRAPHIC METHODS AND PROTOCOLSSylvie Doubli?, EditorCHAPTER TITLE AUTHOR(S) PAGE1. Cryocrystallography of macromolecules: practice and optimisationElspeth Garman and Robin L. Owen 1-242. Determination of reaction intermediates structures in heme proteinsKelvin Chu 1-193. Annealing Macromolecular Crystals Gerard J. Bunick and B. Leif Hanson 1-164. First Analysis of Macromolecular Crystals: Biochemistry and X-ray DiffractionDavid Jeruzalmi 1-325. X-ray Data-Collection from Macromolecular CrystalsElspeth Garman and Robert M. Sweet 1-446. Characterizing your Crystal from an Initial Native Data Set Michael R. Sawaya 1-377. Molecular replacement Eric Toth 1-378. Phase determination using halide ionsMiroslawa Dauter and Zbigniew Dauter 1-119. Multiple isomorphous replacement Mark Rould1-2510. Substructure determination in MAD, SAD, and SIRAS data using Shake-and-Bake (SnB)P. Lynne Howell, G.lƒ,