Mass Spectrometry Data Analysis in Proteomics [Paperback]

Since the publishing of the first edition, the methodologies and instrumentation involved in the field of mass spectrometry-based proteomics has improved considerably.? Fully revised and expanded, Mass Spectrometry Data Analysis in Proteomics, Second Edition presents expert chapters on specific MS-based methods or data analysis strategies in proteomics. The volume covers data analysis topics relevant for quantitative proteomics, post translational modification, HX-MS, glycomics, and data exchange standards, among other topics.? Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Updated and authoritative, Mass Spectrometry Data Analysis in Proteomics, Second Edition serves as a detailed guide for all researchers seeking to further our knowledge in the field of proteomics.This Methods in Molecular Biology book covers mass spectrometry data analysis in quantitative proteomics, post translational modification, HX-MS, glycomics, and data exchange standards. Includes materials lists, reproducible protocols, tips and more.

1. Introduction to Mass Spectrometry-Based Proteomics

??????????? Rune Matthiesen and Jakob Bunkenborg

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2. LC-MS Spectra Processing

??????????? Rune Matthiesen

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3. Isotopic Distributions

??????????? Alan L. Rockwood and Magnus Palmblad

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4. Retention Time Prediction and Protein Identification

??????????? Alex A. Henneman and Magnus Palmblad

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5. Algorithms for Database Dependent Search of lÓ)