This vibrant collection delivers a laboratory roadmap of testing cognition in the rodent. While rodents and mazes are the main center and focus of this book, many aspects in the field of learning and memory are discussed and detailed, spanning from the molecular to the human, with every chapter delivering a comprehensive review of historical milestones in order to provide context for past discoveries, new findings, and future studies. Didactic foundations, operational definitions, and theory, as well as practical experimental and apparatus set-up, data analysis, and interpretation instructions are included in the first part of the book, while part two contains step-by-step protocols, troubleshooting, and tips from experts in the field.
Authoritative and inspirational,
The Maze Book: Theories, Practice, and Protocols for Testing Rodent Cognition serves as a detailed and practical manual for scientists wishing to implement these tools in their laboratories and for scholars interested in this powerful field.
Part I: Why? Foundations of Rodent Learning and Memory: Milestones, Mazes, and Mechanisms
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1. Rodent Mazes and Memory: Continuing the Search for the Engram
??????????? Heather A. Bimonte-Nelson
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2. The Mazes
??????????? Heather A. Bimonte-Nelson, Jill M. Daniel, and Stephanie Koebele
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3. The Watermaze
??????????? Richard G.M. Morris
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4. Behavioral Consequences of Early Disruption and Injury to the Developing Brain: Studying Rodent Models
??????????? Dongnhu T. Truong and R. Holly Fitch
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5. Insights into Age-Related Cognitive Decline: Coupling Neurophysiological and Behavioral Approaches
??????????? Lesley A. Schimanski and Carol A. Barnes
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