Medicinal Applications of Coordination Chemistry RSC [Hardcover]

Metals in pharmaceuticals have played an increasingly important role in medicine in cancer therapy and diagnostic imaging methods. This book focuses on the role that transition metals play in clinical applications and begins with a brief historical review of the chemistry of d- and f- block metals. Subsequent sections discuss metallodrugs for a number of different applications, the design of new drugs and the relationship between structure and function. Diagnostic applications of metal compounds in anatomical and functional imaging, and therapeutic applications of metals compounds are explained. Ideal for both academia and industry and includes examples of real-life applications!The section on platinum, like the others, is in general well illustrated with line diagrams of chemical structures, and gives a good coverage of new developments, such as active trans complexes and potent di- and tri-Pt anticancer complexes.This book will serve a useful role in teaching inorganic chemistry to both undergraduate and postgraduate students. The topic helps to 'bring inorganic chemistry to life' and in my experience does arouse their curiosity at all levels. It will be a useful addition to libraries.In my opinion Jones and Thornback have accomplished their goal, and I am pleased to recommend Medicinal Applications of Coordination Chemistry to pharmacists, clinicians and medical researchers who use metal-containing drugs in a clinical environment. It should also serve as an introductory text for students of chemistry who wish to learn about an aspect of their subject within an applied context rather than just as a subject in its own right.Metals in pharmaceuticals have played an increasingly important role in medicine over the last century, particularly in cancer therapy and diagnostic imaging methods. Medicinal Applications of Coordination Chemistry focuses on the role that transition metals play in clinical applications. Medicinal Applications of Coordination Chemistry beginls+