This fourth volume in a series devoted to cancer treatment discusses various methodologies for the diagnosis, therapy and prognosis of colorectal cancer. It covers the latest information including standard and emerging therapies and technological advances.
Authors and Co-Authors of Volume 4 Preface Contents of Volume 1, 2, and 3 PART I. COLORECTAL CANCER 1. INTRODUCTION: COLORECTAL CANCER M.A. Hayat INTRODUCTIONScreening for Colorectal CancerTreatmentRectal CancerREFERENCESA. Diagnosis 2. POORLY DIFFERENTIATED COLORECTAL ADENOCARCINOMA: (METHODOLOGY) Seiichi Shinji, Zenya Naito, Toshiyuki Ishiwata, Yoko Matsuda, Tomoko Seya, and Takashi Tajiri INTRODUCTIONHISTOPATHOLOGYIMMUNOHISTOCHEMISTRY FOR DIFFERENTIAL DIAGNOSISIMMUNOHISTOCHEMISTRY FOR MALIGNANT CHARACATERISTICS OF POORLY DIFFERENTIATED ADENOCARCINOMAIN SITU HYBRIDIZATION FOR MALIGNANT CHARACTERISTICS OF POORLY DIFFERENTIATED ADENOCARCINOMATHERAPYREFERENCES 3. COLORECTAL CANCER: IMMUNOHISTOCHEMICAL; DIAGNOSIS WITH HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K Ayham Alnabulsi, Brian Carpenter, Colin Telfer, and Graeme I. Murray INTRODUCTIONBIOMARKERSApproved Biomarkers ProblemsBiomarkers of Colorectal CancerDemand for Colorectal BiomarkersCOLORECTAL BIOMARKER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN KMethodology2D Gel Electrophoresis (2DGE)Semiquantitative Reverse Transcription-Polymerase Chain ReactionMonoclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein KImmunohistochemistry (IHC)RESULTSDISCUSSIONFUTURE DIRECTIONREFERENCES 4. METASTASES AND RECURRENCE OF COLORECTAL CANCER: DIAGNOSTIC ROLE OF IMMUNOSCINTIGRAPHY Vladimir Obradovic and Vera Artiko INTRODUCTIONGENERAL CONSIDERATIONSRadiopharmaceuticalsImaging Systems and TechniquesIMMUNOSCINTIGRAPHIC METHODS USED FOR DIAGNOSTICS OFCOLORECTAL CANCERImmunoscintigraphy Based onRadiopharmaceuticals Labeled with RadioiodinesImmunoscintigraphy Based on Radiopharmaceuticals Labeled with 111InImmunoscintigraphy Based on Radiopharmaceuticall3P