Microbial Production From Genome Design to Cell Engineering [Paperback]

Microbial production: From genome design to cell surface engineering affords a comprehensive review of novel technology and approaches being implemented for manufacturing microorganisms, written by specialists in both academia and industry.?This book is divided into three sections: the first includes technology for improvement of fermentation strains and many supporting technologies and information; the second examines novel technology useful for analysis of cell activities, analyzing gene function, and designing genomes of producer strains; and finally, a discussion of the practical application of the techniques and success case studies in many fields of bio-production, such as?microbiological production, pharmaceuticals, chemicals, foods and cosmetics.

This presentation of breeding fermentation strains of microbes has applications in a range of industrial contexts. Leading researchers describe their cutting-edge use of omics information and explain the concept of designing a fermentation-strain genome.

Preface.- Part1: Minimum Genome Factory.- Chapter1Creation of novel technology for extracellular protein production towards the development of Bacillus subtilis genome factories.- Chapter2 Minimum genome factories in Schizosaccharomyces pombe.- Chapter3 Minimum genome Factrotry of E. coli.- Part 2: Whole Genome Manipulation for Genome Design.- Chapetr4 Efficient and accurate production of de novo designed gene clusters of large size by a novel Bacillus subtilis based BGM system.- Chapter5 Development and application of novel genome technology in Saccharomyces cerevisiae.- Chapter6 Genome design of Actinomycetes for secondary metabolism.- Part 3: Application of Omics Information and Construction of Mutant Libraries.- Chapter7 Application methodology of whole omics information.- Chapter8 Appl&