Modification of Cell to Cell Signals During Normal and Pathological Aging [Paperback]

The aging process involves changes in neurotransmission at different levels. The purpose of this book is to help define the state-of-the-art of the field and to give directives for future research on the aging brain. Following topics are presented: the comparison of normal and pathological aging at the anatomical and neurochemical level; the knowledge of the responses of the aging brain to drug treatment or environmental stress; the neuro/immune and neuro/endocrine setting during aging; and the definition of therapeutical approaches in normal aging. This book will interest physicians and pathologists as well as neurophysiologists.Proceedings of the NATO Advanced Research Workshop on Modification of Cell to Cell Signals during Normal and Pathological Aging held at Salo, Garda Lake, Italy, September 22-27, 1986The aging process involves changes in neurotransmission at different levels. The purpose of this book is to help define the state-of-the-art of the field and to give directives for future research on the aging brain. Following topics are presented: the comparison of normal and pathological aging at the anatomical and neurochemical level; the knowledge of the responses of the aging brain to drug treatment or environmental stress; the neuro/immune and neuro/endocrine setting during aging; and the definition of therapeutical approaches in normal aging. This book will interest physicians and pathologists as well as neurophysiologists.Functional Morphology and Cerebral Metabolism During Normal and Pathological Aging.- Functional morphology of neurons during normal and pathological ageing.- Functional morphology during normal and pathological ageing with emphasis on peptidergic transmission.- P.E.T. study of human brain metabolism in aging and dementia.- An experimental approach to the study of the functional derangement which follows aging of the brain and dementia.- Alzheimers disease causes metabolic uncoupling of associative brain regions beyond that seen in the ls+