Molecular Profiling Methods and Protocols [Paperback]

This second edition provides an update on technology and an accelerated tutorial to assist, students, entrepreneurs, new investigators, and established investigators who want to quickly become versed in, and immersed in, the entire process from discovery to clinical trial validation and commercial public benefit.  Chapters aim to cover the full spectrum of molecular profiling from tumor staging and grading through biomarker discovery, to commercialization. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Molecular Profiling: Methods and Protocols, Second Edition aims to be a useful guide on molecular profiling. 

1.  Tumor Staging and Grading: A Primer

Stacy M. Telloni

 

2. Innovations in Clinical Trial Design in the Era of Molecular Profiling

Julia D. Wulfkuhle, Alexander Spira, Kirsten H. Edmiston, and Emanuel F. Petricoin

 

3. Personalized Medicine: Ethical Aspects

Michele Signore, Valeria Manganelli and Alex Hodge

 

5. Scanning Electron Microscopy Sample Preparation and Imaging

Jenny Ngoc Tran Nguyen and Amanda M. Harbison

 

Claudius Mueller, Michael G. Harpole, and Virginia Espinl3Ä