Molecular Testing in Cancer [Hardcover]

Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed next generation analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers.

Written by experts in the field, Molecular Testing in Cancer serves as a useful and comprehensive resource for pathologists, hematologists, laboratory technicians and molecular scientists.

Part 1: Molecular approaches and techniques

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Chapter 1: Transitioning Diagnostic Molecular Pathology to the Genomic Era: Cancer Somatic Mutation Panel Testing

Kitchener D. Wilson and Iris Schrijver

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Chapter 2: Conventional and Molecular Cytogenetics in Cancer

Michelle Dolan

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Chapter 3: Comparative Genomic Hybridization and Array based CGH in Cancer

Roland Hubaux, Victor D. Martinez, David Rowbotham, and Wan L. Lam

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Chapter 4: Polymerase Chain Reaction

Maria Pasic, Carlo Hojilia, and George M. Yousef

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Chapter 5: Single Nucleotide Polymorphisms (SNPs)

Jyotsna Batra, Srilakshmi Srinivasan, and Judith Clements

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Chapter 6: Clinical Application of DNA Sequencing: Sanger and Next-Generation Platforms

John D. McPherson

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Chapter 7: Microarray-based Investil“$