Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.
Part I.
Introduction 2
Understanding Structural Diagrams of Organic Molecules 4
Some Common Molecules 23
Proteins and Three-Dimensional Protein Structure 26
Some of the Protein Structures That Appear in This Book 32
Part II. Inflammatory, Cardiovascular and Metabolic Diseases
Anti-Inflammatory Agents
Acetylsalicylic acid (AspirinTM) 38
Naproxen (AleveTM) 39
How Do Anti-Inflammatory Drugs Work? 40
Other Eicosanoids in Inflammation 41
An Overview of Inflammation 42
Celecoxib (CelebrexTM) 43
Prednisone (DeltasoneTM) 44
Methotrexate (TrexallTM) 46
Allopurinol (ZyloprimTM) 47
Antiasthmatic and Antiallergic Agents
Salmeterol (SereventTM) 50
Fluticasone Propionate (FloventTM) 51
Montelukast Sodium (SingulairTM) 52
Tiotropium Bromide (SpirivaTM) 53
Loratadine (ClaritinTM) 54