NMR of Biological Macromolecules [Paperback]

Provided here are the latest techniques of NMR as applied to the study of proteins, carbohydrates and nucleic acids.
The first chapters are devoted to an introduction to NMR and parameters related to molecular structure and molecular interactions. NMR experiments from basic 1D to 2D, 3D and 4D, used in combination with isotopically labelled molecules, are described and a general strategy is presented for biomacromolecular structure determination. Subsequent chapters deal with more advanced principles and techniques and their applications to structural and dynamic processes involving biomacromolecules in solution. Advanced results on peptide, protein, oligosaccharide and nucleic acid structure and recognition are presented.Proceedings of the NATO Advanced Study Institute on NMR of Biological Macromolecules, held at Kolympari, Crete, August 23 - September 2, 1993Provided here are the latest techniques of NMR as applied to the study of proteins, carbohydrates and nucleic acids.
The first chapters are devoted to an introduction to NMR and parameters related to molecular structure and molecular interactions. NMR experiments from basic 1D to 2D, 3D and 4D, used in combination with isotopically labelled molecules, are described and a general strategy is presented for biomacromolecular structure determination. Subsequent chapters deal with more advanced principles and techniques and their applications to structural and dynamic processes involving biomacromolecules in solution. Advanced results on peptide, protein, oligosaccharide and nucleic acid structure and recognition are presented.Basic Pulsed NMR Experiments.- Principles of Multidimensional NMR.- Understanding Pulsed FTNMR Experiments.- Computer  Assisted Structure Determination of Biomacromolecules by NMR.- Nuclear Shielding and Biomolecular Structure.- NMR Studies of Protein Ligand Interactions.- NMR Studies of Ligand  Protein Interactions Involving Quadrupolar Nuclei.- Multidimensional NMR Spel#g