This book intends to be an easy and concise introduction to the field of nuclear magnetic resonance or NMR, which has revolutionized life sciences in the last twenty years. A significant part of the progress observed in scientific areas like Chemistry, Biology or Medicine can be ascribed to the development experienced by NMR in recent times. Many of the books currently available on NMR deal with the theoretical basis and some of its main applications, but they generally demand a strong background in Physics and Mathematics for a full understanding. This book is aimed to a wide scientific audience, trying to introduce NMR by making all possible effort to remove, without losing any formality and rigor, most of the theoretical jargon that is present in other NMR books. Furthermore, illustrations are provided that show all the basic concepts using a naive vector formalism, or using a simplified approach to the particular NMR-technique described. The intention has been to show simply the foundations and main concepts of NMR, rather than seeking thorough mathematical expressions.
This book offers a concise introduction to the field of nuclear magnetic resonance or NMR. It presents the basic foundations of NMR in a non-mathematical way and provides an overview of both recent and important biological applications of NMR.
1. The basis of Nuclear Magnetic Resonance Spectroscopy
1.1. Introduction
1.2. Physical principles of NMR spectroscopy
1.2.1. The basis of NMR spectroscopy: a vector approach
1.2.2. The basis of NMR spectroscopy: a na?ve quantum approach
1.2.3. The nuclei in NMR
1.3. Spin relaxation
1.3.1. Spin-lattice relaxation time
1.3.2. Spin-spin relaxation time
1.3.3. Sources of variation in local fields
1.4. Pulse techniques
1.4.1. How a pulse works: the time and frequency domains
1.4.2. Multipulse experiments: measulĂȘ