This volume is a state-of-the art resource on the recent advances and clinical management of NSAIDs and aspirin. The text provides a thorough overview of NSAIDS and aspirin, reviewing such topics as pharmacology and mechanisms, clinical effects, and the safety and efficacy of these drugs. It also focuses on the effect of the drugs on the cardiovascular system and in the prevention of GI cancer. Practical recommendations for a safe prescription of NSAIDs are also included.
Written by experts in the field, NSAIDs and Aspirin: Recent Advances and Implications for Clinical Management is a comprehensive text of great value to gastroenterologists, rheumatologists, cardiologists, oncologists, orthopedists, trauma and internal medicine specialists.
Section 1. Pharmacology and Mechanisms
Chapter 1. Chemistry, Pharmacodynamics, and Pharmacokinetics of NSAIDs
Sara Calatayud and Juan Vicente Esplugues
Chapter 2. Principles, Mechanisms of Action, and Future Prospects of Anti-Inflammatory Drugs
Bibiana Rius and Joan Cl?ria
Section 2. Clinical Effects and Drug Safety
Chapter 3. Efficacy of NSAIDs in the Treatment of Rheumatic Diseases
Marc C. Hochberg and Lee S. Simon
Chapter 4. Adverse Effects of NSAIDs in the Gastrointestinal Tract: Risk Factors of Gastrointestinal Toxicity with NSAIDs
Sunny H. Wong and Francis K.L. Chan
Chapter 5. Adverse Effects of NSAIDs on the Cardiovascular System
Carmelo Scarpignl£*