The Nucleolus [Hardcover]

Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role.?The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.Extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality.? This book examines these recent discoveries. It emphasizes nucleolar proteins while also including the crucial importance of nucleic acids.

Acknowledgements
Preface

Part 1:? Nucleolar Structure and Organization
1.?Structural organization of the nucleolus as a consequence of the dynamics of ribosome biogenesis
Dani?le Hernandez-Verdun

2.?The dynamic? proteome of the nucleolus
Fran?ois-Michel Boisvert, Yasmeen Ahmad, Angus I. Lamond

3.?The Structure of rDNA Chromatin
Peter C McKeown, Peter J Shaw

4.?The epigenetics of the nucleolus: structure and function of active and silent ribosomal RNA genes
Raffaella Santoro

5.?UBF, an Essential Player in Maintenance of Active NORs and nucleolar formation
Alice Grob, Christine Colleran, Brian McStay

Part 2:? Role of the Nucleolus in Ribosome Biogenesis
6.?The RNA Polymerase I Transcription Machinery
Renate Voit, Ingrid Grummt

7.?Small Ribonucleoproteins in Ribosome Biogenesis
Franziska Bleichert, Susan Baserga

8.?Crosstalk between ribosome synthesis and cell cycle progression and its potential implications in? human genetic disease
Marie G?rus, Mich?le Caizergues-Ferrer, Yves Henry, Anthony Henras

9.?The multipl#