Here is an exhaustive exploration of all aspects of research on organelle genomes. This outstanding new volume reviews the properties of chloroplast and mitorchondrial genomes, describing in depth their structure, gene content, expression, evolution, and genetics.
The book takes readers to the outer limits of contemporary research, showing how the study of genomes contributes to the solution of important problems in molecular biology. It covers a wide range of problems from the use of organelle DNA molecules in taxonomic and phylogenetic studies to molecular investigations of the mechanisms underlying RNA editing, intron splicing and mobility, protein import, and mitochondrial disease.
This unique text is designed for an introductory course in organelle genetics at the graduate or advanced undergraduate level. It is of special interest to professionals in the fields of molecular and cell biology, genetics, and evolution.
Part I: Introduction to Chloroplasts and Mitochondria 1. Chloroplasts and Mitochondria Part II: Evolution and Organization of Organelle Genomes 2. Endosymbiotic Origin of Chloroplasts and Mitochondria 3. Organelle Genome Organization and Gene Content 4. Evolution of Organelle Genomes 5. Cytological Organization and Replication of Organelle Genomes 6. Phylogenetic Uses of Organelle DNA Variation Part III: Organelle Genetics 7. Model Systems and Gene Manipulation 8. Transmission and Compatibility of Organelle Genes 9. Intracellular Genetics of Organelles 10. Introns, Mobile Elements and Plasmids 11. Mitochondrial Disease Part IV: Expression and Biogenesis 12. Transcription and mRNA Processing in Organelles 13. Protein Synthesis in Organelles 14. Reading and Editing Messages in Chloroplasts and Mitochondria 15. Protein Targeting and Import 16. Control of Gene Expression in Chloroplast Biogenesis 17. Conl½