Organic Transistor Devices for In Vitro Electrophysiological Applications [Hardcover]

This thesis reports on a novel system forextracellular recordings of the activity of excitable cells, which relies on anorganic, charge-modulated field-effect transistor (FET) called OCMFET. Thebook shows how, thanks to the intrinsic biocompatibility, lightness, andinexpensiveness of the material used, this new system is able to overcome severalproblems typical of of classic electronic andbioelectronic. Itprovides a full description of the system, together with a comprehensive reportof the successful experimental trials carried out on both cardiac and nervecells, and a concise yet comprehensive overview of bioelectronic interfaces andorganic sensors for electrophysiological applications.

 

Introduction.- Bio-electronics Interfaces.- Organic Devices for Electrophysiological Applications.- The Micro Organic Charge Modulated FET Array.- Experimental Results.-Conclusions.

This thesis reports on the Micro OCMFET Array, a novel, reference-less

system for extracellular recordings of action potentials. The book 

provides readers with a full description of the system, together with an

extensive report of the successful experimental trials carried out on both

cardiac and nerve cells. Moreover, it offers a concise yet comprehensive

overview of both bioelectronic interfaces, such as Micro Electrode Arrays

(MEAs) and Field Effect Devices (FEDs), and organic sensors for electro-

physiological applications, including Organic Charge-Modulated FETs

(OCMFET), Electrolyte-Gated Organic FETs (EGOFETs), and Organic

Electrochemical Transistors (OECTs).

Nominated as an outstanding PhD thesis by the University of Genoa, Italy

Reports on the design and implemel÷